ASH 2010: Large International Study Backs Use of Imatinib in Adults With Ph ALL
March 10th 2011Imatinib (Gleevec) improves the ability to proceed with allogeneic stem cell transplantation and improves 5-year overall survival (OS) when used as induction therapy in patients with Philadelphia chromosome positive (Ph ) acute lymphoblastic leukemia
ASH 2010: Ponatinib Inhibits Mutations That Block Treatment Paths for CML, ALL, and AML
March 10th 2011An investigational pan-BCR-ABL inhibitor designed to inhibit the entire spectrum of mutations responsible for resistance to drugs such as imatinib (Gleevec) and its cousins nilotinib (Tasigna) and dasatinib (Sprycel) appears to fulfill its promise.
Modified Herpes Virus to Be Tested in Sarcoma Patients
March 9th 2011The FDA has awarded a $600,000 grant for a phase I clinical trial of a genetically reprogrammed herpes simplex virus in young cancer patients with relapsed non-central nervous system (CNS) solid tumors such as sarcomas and neuroblastomas.
Lung Cancer Screening Test Raises Hopes and Sets Stage for Discussion of Guidelines
March 9th 2011Lung Cancer Screening Test Raises Hopes and Sets Stage for Discussion of Guidelines The Lung Cancer Alliance is pressing for a full discussion about the guidance on whether people at high risk for lung cancer should undergo screening
NCCN Launches Consumer-Friendly Versions
March 9th 2011NCCN Launches Consumer-Friendly Versions of Guideline Publications Breast cancer and non-small cell lung cancer are the inaugural entries in a new series of publications the National Comprehensive Cancer Network (NCCN) is rolling out in the coming months.
Oncology Community Must Guide Public on Gene Testing Nuances
March 8th 2011The genuine revolution in our understanding of the genetic basis of malignant disease has led to a corresponding interest in defining the risk of developing a particular disease for both individuals and specific populations.
ASH 2010: Brentuximab Showing Promise as Hodgkin Lymphoma Therapy
March 8th 2011An investigational drug known as brentuximab vedotin (SGN-35) achieved dramatic responses in a phase II study of younger patients with relapsed or refractory Hodgkin lymphoma (HL) who had no other treatment options