Dr Locke Shares Key Takeaways from ZUMA-7 and TRANSFORM Studies

EP: 1.Navigating Second-Line Treatments and CAR T-Cell Therapy for DLBCL: Insights from Dr. Budde and Dr. Lunning

EP: 2.Dr Locke, Dr Hunter, Dr Lunning Share Referral Patterns in Their Practices

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EP: 3.Dr Locke Shares Key Takeaways from ZUMA-7 and TRANSFORM Studies

EP: 4.Dr Gordon Shares Key Takeaways from ALYCANTE and PILOT for 2L CAR T-cell Transplant-Ineligible Population

EP: 5.Dr Hunter Shares Key Takeaways from L-MIND 5-Year Data and RE-MIND2 Study

EP: 6.Panel Discuses Use of CD19 Bispecifics in Sequencing

EP: 7.Panel Discusses Challenges with CAR T Therapy in R/R DLBCL, Particularly Around T-cell Exhaustion

EP: 8.Current Approach to Bridging Therapy in R/R DLBCL

EP: 9.Risk of Secondary Malignancies in Heavily Pre-Treated Population

EP: 10.Management of CRS and ICANS with CAR T-cell Therapy

EP: 11.Third-line Treatment Options for DLBCL After CAR T-cell Therapy or ASCT in Second-line

EP: 12.Contemporary Sequencing CD20xCD3 Bispecific Antibody R/R DLBCL Who Have progressed beyond CAR T-cell therapy

EP: 13.Bispecific therapy – treatment setting and management of short-term adverse events

EP: 14.Bispecific therapy – management of long-term adverse events in the community setting

EP: 15.Practice Patterns and Real Use of Epcoritamab and Glofitamab

EP: 16.Disparities in access to newer or expensive treatments, unmet needs in the treatment of DLBCL

Video content above is prompted by the following:

• Please discuss the data supporting CAR T-cell therapy as the primary 2Ltreatment option for patients who are transplant-eligible and have primary refractory or early relapse R/R DLBCL.
  • Please review the latest 56-month follow-up data of the ZUMA-7study, evaluating axi-cel.
    • ASH 2024 Update: Subgroup Analysis of the ZUMA-7 study.
    • Please discuss the subsequent cellular immunotherapy off-protocol in the SOC arm.
• Please review the 36-month follow-up data of the TRANSFORM study, evaluating liso-cel.
  • ASCO 2024 Update: Subgroup analysis of the TRANSFORM study [primary refractory vs. early relapsed].
• What were some key takeaways from the results of these two studies?