Video

ESMO 2021 Updates in Metastatic Esophageal Squamous Cell Carcinoma

Author(s):

Sam Klempner, MD, Massachusetts General Hospital ,Daniel H. Ahn, DO, Mayo Clinic

Experts in gastrointestinal cancers review recent updates and clinical implications from phase 3 trials presented at ESMO 2021 in metastatic esophageal squamous cell carcinoma (ESCC).

Data from the following clinical trials are discussed:

  • 1373M0 - JUPITER-06: A randomized, double-blind, phase 3 study of toripalimab versus placebo in combination with first-line chemotherapy for treatment naive advanced or metastatic esophageal squamous cell carcinoma (ESCC) (JUPITER-06)
  • LBA52 - Sintilimab plus chemotherapy versus chemotherapy as first-line therapy in patients with advanced or metastatic esophageal squamous cell cancer: First results of the phase 3 ORIENT-15 study (ORIENT-15)
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