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Opinion|Videos|September 30, 2024

Key Findings from the PRIMA Trial: Niraparib in 1L Maintenance for Advanced Ovarian Cancer

Author(s)Angeles Alvarez Secord, MD, MHSc , Dana M. Chase, MD, FACOG, Bhavana Pothuri, MD

Panelists discuss optimal durations for PARP inhibitor maintenance therapy in ovarian cancer, exploring how long patients are typically kept on PARPi in both first-line and second-line maintenance settings.

Episodes in this series

5 KOLs are featured in this series.

EP. 1 Approaching Biomarker Testing and Frontline Maintenance Therapy for Advanced Ovarian Cancer

5 KOLs are featured in this series.

EP. 2 Key Findings from the PRIMA Trial: Niraparib in 1L Maintenance for Advanced Ovarian Cancer

5 KOLs are featured in this series.

EP. 3 Duration of PARP Inhibitor Maintenance Therapy for Ovarian Cancer

5 KOLs are featured in this series.

EP. 4 Emerging Combinations in Maintenance Therapy for Ovarian Cancer

5 KOLs are featured in this series.

EP. 5 Optimizing Ovarian Cancer Care: PARP Resistance, Management of Oligoprogression, and Adverse Event Mitigation

5 KOLs are featured in this series.

EP. 6 Use of Trastuzumab Deruxtecan in Ovarian Cancer

5 KOLs are featured in this series.

EP. 7 Antibody-Drug Conjugates in Ovarian Cancer: Emerging Data and Treatment Integration

5 KOLs are featured in this series.

EP. 8 Navigating Treatment Strategies for Advanced Cervical Cancer: Localized Therapy, KEYNOTE-A18 Trial Data, and Frontline Approaches

5 KOLs are featured in this series.

EP. 9 Integrating Tisotumab Vedotin into Ovarian Cancer Therapy

5 KOLs are featured in this series.

EP. 10 Biomarker Testing in Advanced Endometrial Cancer: Approach, Key Markers, and Impact on Treatment Decisions

5 KOLs are featured in this series.

EP. 11 Managing Recurrent Endometrial Cancer: Treatment Strategies and RUBY Trial Insights

5 KOLs are featured in this series.

EP. 12 Durvalumab in Endometrial Cancer: DUO-E Trial Updates

5 KOLs are featured in this series.

EP. 13 Innovative Combination Strategies for Endometrial Cancer: Updates from LEAP and KEYNOTE-B21 Trials

5 KOLs are featured in this series.

EP. 14 T-DXd in Advanced Endometrial Cancer

5 KOLs are featured in this series.

EP. 15 Emerging ADCs in Advanced Endometrial Cancer: Anti-TROP2 and Anti-FR Agents

Video content above is prompted by the following:

Briefly comment on key findings and final OS data from the PRIMA trial, evaluating niraparib 1L maintenance therapy in newly diagnosed advanced ovarian cancer.
What implications do these findings have and what impact may they have on the treatment paradigm for ovarian cancer?
What new insights can be drawn about long-term responders to maintenance niraparib from the recent subanalysis of the GEICO-88R study?

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