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Paolo Caimi, MD, discusses the rationale behind evaluating LMY-920, a novel BAFF CAR T-cell therapy, in relapsed/refractory non-Hodgkin lymphoma.

Dr Caimi on Early Data for LMY-920 in R/R B-Cell NHL

David H. Aggen, MD, PhD, details the evolving landscape of treating patients with urothelial carcinoma.

Navigating a “Sea Change” in Frontline Urothelial Carcinoma Treatment

Jennifer Scalici, MD, discusses data for IMNN-001plus chemotherapy in advanced ovarian cancer.

Dr Scalici on Data for IMNN-001 Plus SOC Chemotherapy in Advanced Ovarian Cancer

Steven H. Lin, MD, PhD, discusses the safety of NKTR-255 in enhancing immune recovery post-chemoradiation in locally advanced NSCLC.

Dr Lin on the Safety of NKTR-255 in Enhancing Immune Recovery Post-Chemoradiation in Locally Advanced NSCLC

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David R. Oveisi, MD, discusses how the expanded indications for ide-cel and cilta-cel are affecting treatment decision-making in multiple myeloma.

Expanded Indications for CAR T-Cell Therapies Shepard in New Era of Myeloma Care

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Alberto Montero, MD, MBA, CPHQ, discusses the potential role for STX-478 in PIK3CA-mutant breast and gynecologic cancers. 

STK-478 May Be an Effective, Tolerable Treatment Alternative in PIK3CA-Mutant Breast and Gynecologic Cancers

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Zorifertinib has received NMPA approval in the first line for EGFR-mutant advanced or metastatic non–small cell lung cancer displaying CNS metastases.

Zorifertinib Receives NMPA Approval for EGFR+ NSCLC With CNS Metastases

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The FDA has approved revised drug labeling for fludarabine phosphate under Project Renewal.

FDA Approves New Drug Labeling for Fludarabine Phosphate in CLL

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ASK THE EXPERTS: Advanced Neuroimaging of Glioblastoma

Clinical

Video Series

Navigating Glioblastoma Imaging: The Patient Journey from Diagnosis to Treatment 

Videos

Nathalie Albert, MD, and Matthias Preusser, MD, explore the latest advancements in neuroimaging technologies and techniques, focusing on the use of amino acid tracers to enhance the diagnosis, treatment, and overall care of patients with glioblastoma.

Nathalie Albert, MD, and Matthias Preusser, MD engage in an interactive discussion about the primary challenges in neuroimaging for glioblastoma patients and provide an overview of the disease.  

Neuroimaging of Glioblastoma 

Key opinion leaders discuss the patient journey, highlighting the clinical course of the disease and the corresponding imaging needs at each stage, such as identification of biopsy site, delineation of tumor, and differentiation of response from treatment-related effects.  

Medical experts discuss the use of various neuroimaging techniques, such as MRIs, CT scans, and PET scans, emphasizing that due to limitations of MRI it is frequently combined with other modalities to obtain more comprehensive information.

Leveraging Neuroimaging Modalities and Guidelines in Glioblastoma

Experts engage in a comprehensive discussion on conventional imaging techniques, evaluating the strengths and limitations of CT and MRI scans, particularly in delineating tumor borders and distinguishing between tumors and the surrounding central nervous system tissue.

Conventional Neuroimaging: CT scans & MRI Scans in Glioblastoma

Nathalie Albert, MD, delves into advanced MRI techniques such as perfusion imaging, functional MRI, MR spectroscopy, and DEMARCATE, while also exploring the role of PET imaging, particularly those utilizing glucose and amino acid tracers in neuroimaging.

Advanced Modalities of Neuroimaging in the Management of Glioblastoma

Nathalie Albert, MD, explains that amino acid PET scans can be valuable tools in monitoring disease progression and assessing a patient's response to treatment, while also exploring the optimal timing for utilizing these scans in the overall management of brain tumors.

Polling Question: Utility of Amino Acid PET

Medical experts engage in a discussion on the PET RANO 1.0 Response Criteria, which provides guidelines for evaluating treatment response in patients with brain tumors, taking into account both measurable PET-positive disease and non-PET-positive disease, as assessed through initial baseline imaging and subsequent follow-up scans. 

Implementing PET RANO 1.0 Response Criteria in Glioblastoma Assessment 

Nathalie Albert, MD, and Matthias Preusser, MD, address audience questions and share their insights on promising and anticipated advancements in neuroimaging techniques, highlighting the potential impact of these emerging strategies on the diagnosis, monitoring, and treatment of glioblastoma. 

Navigating Glioblastoma Imaging: The Patient Journey from Diagnosis to Treatment

EP: 1.Neuroimaging of Glioblastoma

EP: 2.Navigating Glioblastoma Imaging: The Patient Journey from Diagnosis to Treatment

EP: 3.Leveraging Neuroimaging Modalities and Guidelines in Glioblastoma

EP: 4.Conventional Neuroimaging: CT scans & MRI Scans in Glioblastoma

EP: 5.Advanced Modalities of Neuroimaging in the Management of Glioblastoma

EP: 6.Polling Question: Utility of Amino Acid PET

EP: 7.Implementing PET RANO 1.0 Response Criteria in Glioblastoma Assessment

EP: 8.Q&A: Final Questions on Glioblastoma and Neuroimaging

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