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Patient Selection and Sequencing of NSCLC ADCs

The panel examines which patient populations might benefit most from treatment with datopotamab deruxtecan (Dato-DXd), sacituzumab govitecan, and patritumab deruxtecan (HER3-DXd). Additionally, they explore potential sequencing strategies for these antibody-drug conjugates in second-line and later treatment settings.

  • Discuss which patients are potentially most suitable for:
    • Dato-DXd
    • Sacituzumab govitecan
    • HER3-DXd
  • With the potential approval of multiple ADCs in second line and beyond, how might these be sequenced in your clinical practice?
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