Opinion

Video

The EMBARK trial investigating enzalutamide in NM CSPC

Author(s):

Stephen J. Freedland, MD,Eleni Efstathiou, MD, PhD

Prostate cancer experts analyze the EMBARK trial, emphasizing the potential impact of an androgen receptor inhibitor in the treatment of non-metastatic castration-sensitive prostate cancer.

  1. Dr. Efstathiou asks Dr. Freedland: Enzalutamide is currently the only androgen receptor inhibitor approved for non-metastatic CSPC. Can you summarize the key data from the EMBARK trial supporting its use in this setting?
    1. Please comment of the high risk study population evaluated in the EMBARK trial
    2. What were the primary endpoints and efficacy findings from the EMBARK trial? Please also comment on your impressions of the monotherapy arm.
    3. What are your impressions of the safety data from EMBARK?
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