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Opinion|Videos|July 10, 2024

The Role of PSA Doubling Time in Risk Assessment

Author(s)Stephen J. Freedland, MD, Eleni Efstathiou, MD, PhD

Specialists examine non-metastatic castration-sensitive prostate cancer cases, evaluating the significance of PSA doubling time and the reliability of biomarkers in risk assessment for these patients.

Episodes in this series

2 KOLs are featured in this panel.

EP. 1 Testing Principes and Benefits of Early Intervention in Castration-Sensitive Prostate Cancer

2 KOLs are featured in this panel.

EP. 2 Risk Stratification and Prognostic Markers in castration-sensitive prostate cancer

2 KOLs are featured in this panel.

EP. 3 Evolving Treatment Paradigm and NCCN Guideline Updates

2 KOLs are featured in this panel.

EP. 4 The EMBARK trial investigating enzalutamide in NM CSPC

2 KOLs are featured in this panel.

EP. 5 The Role of PSA Doubling Time in Risk Assessment

2 KOLs are featured in this panel.

EP. 6 Patient Case 1: Non-Metastatic CSPC with Rapidly Doubling PSA

Stephen J. Freedland, MD, and Eleni Efstathiou, MD, PhD, experts on prostate cancer

EP. 7 Patient Case 2: Metastatic CSPC

Stephen J. Freedland, MD, and Eleni Efstathiou, MD, PhD, experts on prostate cancer

EP. 8 Final Thoughts on CSPC

Dr. Efstathiou asks Dr. Freedland: In evaluating non-metastatic CSPC cases, what role does PSA doubling time play in your risk assessment?
1. At what PSA doubling time thresholds do treatment recommendations change?
2. How reliable is PSA doubling as a biomarker versus imaging or other tests?

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