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J. Bradley Elder, MD, discusses blinded early-safety data from a phase 2b trial of IGV-001 in patients with newly diagnosed glioblastoma.

Dr Elder on the Initial Safety Profile of IGV-001 in Newly Diagnosed Glioblastoma

Rimas V. Lukas, MD, discusses the efficacy of eflornithine plus lomustine in recurrent IDH-mutant anaplastic astrocytoma per 2021 WHO diagnostic criteria.

Dr Lukas on Survival Outcomes With Eflornithine in IDH-Mutant Anaplastic Astrocytoma 

IGV-001, an autologous cell immunotherapy, demonstrated an acceptable safety profile in patients with newly diagnosed glioblastoma.

IGV-001 Showcases Positive Benefit-Risk Profile in Newly Diagnosed Glioblastoma

Paolo Caimi, MD, discusses the rationale behind evaluating LMY-920, a novel BAFF CAR T-cell therapy, in relapsed/refractory non-Hodgkin lymphoma.

Dr Caimi on Early Data for LMY-920 in R/R B-Cell NHL

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Jairam Krishnamurthy, MD, FACP, details what to take into consideration when implementing 2024 Breast Cancer NCCN guideline changes into everyday practice. 

Category 1 Recommendation of Ribociclib Plus an AI Represents Huge Advancement in Breast Cancer

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Francisco J. Esteva, MD, PhD, highlights various pivotal studies for the treatment of HER2-positive early-stage breast cancer.

Long-Term Findings Solidify Role of HER2-Targeted Therapy in Early HER2+ Breast Cancer

Lu Chen, PhD, an Assistant Professor in the Nuclear Dynamics and Cancer Research Program has received a grant from the NIH to further investigate the role of RNA and the formation of liquid droplet structures within cancer cells.

Fox Chase Cancer Center Researcher Lu Chen Receives $250,000 NIH Grant to Further Investigation of RNA

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Inside the Clinic: Updates in the Prevention and Treatment of Graft versus Host Disease

Videos

Sophie Paczesny, MD, PhD, and Yi-Bin Chen, MD, discuss recent updates in the prophylactic and treatment strategies for acute and chronic graft versus host disease (GVHD).

Sophie Paczesny, MD, PhD, explains which malignancies allogeneic transplantation can be used as a potentially curative treatment approach, and which patients are best suited for transplant.

Indications for Allogeneic Stem Cell Transplantation in the Treatment of Hematological Malignancies

Dr Sophie Paczesny details the incidence of graft versus host disease (GVHD) in patients receiving allogeneic transplants, and Dr Yi-Bin Chen describes the differing risk factors for acute and chronic GVHD.

Incidence and Risk Factors of Acute and Chronic GVHD

Yi-Bin Chen, MD, shares the most common GVHD prophylaxis regimens, and which regimen he typically chooses for his patients with GVHD.

Common Prophylaxis Regimens for GVHD

Drs Yi-Bin Chen and Sophie Paczesny review the diagnosis and staging of both acute and chronic GVHD, and the challenges clinicians may encounter.

Diagnosis and Stratification of Acute and Chronic GVHD

Experts discuss the current options for treating acute GVHD, including the use of corticosteroids and their management.

Frontline Treatment Options for Acute GVHD

Sophie Paczesny, MD, PhD, and Yi-Bin Chen, MD, detail novel strategies under investigation for the treatment of acute GVHD.

Emerging Strategies for the Treatment of Acute GVHD

Drs Paczesny and Chen explain the importance of treating chronic GVHD as early as possible, and whether steroids are still the standard first-line treatment.

The Importance of Early Treatment of Chronic GVHD

Yi-Bin Chen, MD, reviews the treatment options for patients with steroid-refractory chronic GVHD.

Treatment Options for Steroid-Refractory Chronic GVHD

Drs Yi-Bin Chen and Sophie Paczesny highlight data from key investigational approaches presented at recent meetings.

Key Investigational Approaches for Acute and Chronic GVHD

Sophie Paczesny, MD, PhD, and Yi-Bin Chen, MD, share their expert perspectives on how the GVHD treatment landscape is evolving.

The Evolving Field of GVHD Treatment

EP: 1.Indications for Allogeneic Stem Cell Transplantation in the Treatment of Hematological Malignancies

EP: 2.Incidence and Risk Factors of Acute and Chronic GVHD

EP: 3.Common Prophylaxis Regimens for GVHD

EP: 4.Diagnosis and Stratification of Acute and Chronic GVHD

EP: 5.Frontline Treatment Options for Acute GVHD

EP: 6.Emerging Strategies for the Treatment of Acute GVHD

EP: 7.The Importance of Early Treatment of Chronic GVHD

EP: 8.Treatment Options for Steroid-Refractory Chronic GVHD

EP: 9.Key Investigational Approaches for Acute and Chronic GVHD

EP: 10.The Evolving Field of GVHD Treatment

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