New Options Mark Major Strides in Treating HER2+ Metastatic Breast Cancer
September 16th 2020A panel of breast cancer experts discuss a variety of new and emerging agents to treat patients with advanced or metastatic HER2-positive breast cancer with disease progression following treatment with at least 1 anti-HER2 therapy.
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Prompt Diagnosis Is Vital in Treatment of Tenosynovial Giant Cell Tumors
September 1st 2020During an OncLive Peer Exchange®, a panel of orthopedic experts provided a comprehensive overview of these tumors, including their epidemiology and differential diagnosis, optimal clinical workup, and the role of surgical management.
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Evaluating the Nonmetastatic CRPC Landscape: What Have We Learned?
June 18th 2020A panel of experts provide their insights on how and when they are using novel imaging versus conventional imaging. They also discuss the data regarding the FDA-approved AR-targeted therapies, how they select between them, and their strategies for mitigating any adverse events.
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Experts Provide Tips on Harnessing MRD to Guide ALL Therapy
June 4th 2020During a recent OncLive Peer Exchange®, a panel of experts in adult and pediatric leukemia provided insight on how they use minimal or measurable residual disease (MRD) to guide treatment decisions, including transplantation and choice of therapy in patients who demonstrate MRD positivity after induction and first- and subsequent-line therapies.
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Looking Forward to a New Wave of Breast Cancer Therapies
May 14th 2020The degree to which nature and nurture affect disease has long been debated in medicine, and it is an issue that esteemed breast cancer researcher and medical oncologist Joyce A. O’Shaughnessy, MD, has been working to unravel for her patients throughout a career that spans more than 30 years.
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MCL Treatments Step Away From Chemotherapy, Closer to a Cure
April 24th 2020During a recent OncLive Peer Exchange®, a panel of hematologic cancer experts discussed several novel treatments that are changing the relapsed/refractory mantle cell lymphoma treatment landscape, including Bruton tyrosine kinase (BTK) inhibitors, BTK combinations, and chimeric antigen receptor T-cell therapy.
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Fresh Options Are Emerging for Relapsed DLBCL
April 7th 2020Although considerable progress has been made in treating diffuse large B-cell lymphoma since the advent of chemoimmunotherapy, approximately 33% of patients still develop relapsed/refractory disease, which is associated with considerable morbidity and mortality.
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Key Questions Surround CDK4/6 Inhibitors in HR+ Breast Cancer
February 28th 2020During a recent OncLive Peer Exchange®, a panel of experts sought to answer several key questions regarding the management of advanced, hormone receptor–positive breast cancer, particularly with CDK4/6 inhibitors.
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Immunotherapy Opens Doors in Small Cell Lung Cancer
February 2nd 2020Immune checkpoint inhibitors have yielded modest improvement in small cell lung cancer (SCLC), but have already reshaped the management of this tumor type and helped open the door to the exploration of other, potentially more effective treatment approaches, according to a panel of thoracic oncology experts who discussed the treatment horizon for SCLC in a recent OncLive Peer Exchange® panel.
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PARP Inhibitors Gain Importance in Ovarian Cancer Lineup
January 15th 2020PARP inhibitors are poised to acquire a stronger foothold in the frontline setting for advanced ovarian cancer, for which chemotherapy remains the backbone of treatment, according to a panel of gynecologic oncology experts who discussed the issue during an OncLive Peer Exchange® held during the European Society for Medical Oncology Congress 2019.
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Rapid Growth of Targeted Therapies in AML Spurs Need for More Learning
November 14th 2019During a recent OncLive Peer Exchange® program, a panel of leukemia experts provided an overview of these agents and shared their perspectives on how clinicians can incorporate them into their clinical practice.
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Pancreatic Cancer Is Moving Beyond the Tip of the Treatment Iceberg
October 3rd 2019During an OncLive Peer Exchange®, a panel of pancreatic cancer experts discuss how they select between first- and subsequent-line cytotoxic regimens and strategies they use to reduce toxicity, including dose modifications and alternative combinations. They also provide insights on some of the emerging therapies in clinical trials for advanced pancreatic cancer.
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How CDK4/6 Inhibitors Are Shaking Up the Breast Cancer Paradigm
July 28th 2019During a recent OncLive Peer Exchange®, a panel of breast cancer experts discussed how they are using CDK4/6 inhibitors in their practices. They shared their insights on the tolerability and toxicity profiles of the FDA-approved CDK4/6 inhibitors, how they choose which agents to use for each patient, and how they select the next line of therapy after the patient progresses.
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NTRK Gene Fusions: Finding the "Golden Ticket" in Oncology
July 18th 2019During an OncologyLive Peer Exchange, the panelists discuss some of the challenges they face when conducting molecular testing, including determining which patients to test, when to test, and how to test to ensure that no golden tickets, such as NTRK gene fusions, are missed. They also discuss the data surrounding TRK inhibitors and their experiences using these agents.
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Systemic Treatments for NETs: Whom to Treat and How to Sequence
May 2nd 2019During a recent panel discussion, neuroendocrine tumor experts Simron Singh, MD, MPH, and Jonathan R. Strosberg, MD, provided insight on which patients are the best candidates for these approved treatments and how to sequence therapy to optimize outcomes.
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Novel Agents Spark New Approaches for Triple-Negative Breast Cancer
February 15th 2019During a recent OncLive Peer Exchange®, a panel of breast cancer experts discussed emerging agents in triple-negative breast cancer, which include an anti–PD-L1 antibody, 2 PARP inhibitors, and a novel antibody–drug conjugate.
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