Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

CDK4/6 Inhibitors Play a Growing Role in Enhancing Endocrine Therapy

CDK4/6 Inhibitors Play a Growing Role in Enhancing Endocrine Therapy

March 9th 2019

For more than 100 years, endocrine therapy has been used for the treatment of breast cancer; since that time, we have learned much about the role of estrogen in the biology of normal breast cancer development.

Treatment Tailoring Possible With Gene Expression Profiling

Treatment Tailoring Possible With Gene Expression Profiling

March 9th 2019

Each gene expression-based test available for risk prediction in patients with breast cancer has unique properties and they are not interchangeable, placing importance on the clinical studies used to validate the clinical utility of each assay.

Dr. Mittendorf on FDA Approval of Frontline Atezolizumab/Nab-Paclitaxel in PD-L1+ TNBC

Dr. Mittendorf on FDA Approval of Frontline Atezolizumab/Nab-Paclitaxel in PD-L1+ TNBC

March 9th 2019

Elizabeth A. Mittendorf, MD, PhD, director of the Breast Immuno-Oncology Program at Dana-Farber/Brigham and Women's Cancer Center, discusses the frontline approval of atezolizumab in combination with nab-paclitaxel in patients with locally advanced or metastatic PD-L1

Dr. Hurvitz on FDA Approval of Subcutaneous Trastuzumab Formulation in HER2+ Breast Cancer

Dr. Hurvitz on FDA Approval of Subcutaneous Trastuzumab Formulation in HER2+ Breast Cancer

March 9th 2019

Sara A. Hurvitz, MD, director of the Breast Oncology Program, medical director of the Clinical Research Unit, University of California, Los Angeles Jonsson Comprehensive Cancer Center, discusses the recent FDA approval of subcutaneous use of trastuzumab (Herceptin) and hyaluronidase-oysk injection (Herceptin Hylecta) in the HER2-positive breast cancer space.

Getting It Right in Breast Cancer Means Being More Precise

Getting It Right in Breast Cancer Means Being More Precise

March 8th 2019

After nearly 30 years as a breast cancer surgeon, Patrick I. Borgen, MD, finds that the most enduring theme in the field is constant change.

Top Developments in Breast Cancer Research Shape the MBCC Agenda

Top Developments in Breast Cancer Research Shape the MBCC Agenda

March 8th 2019

The breast cancer field is experiencing rapid advancements in the understanding of disease biology and the development of novel therapeutic strategies for several subtypes, with a clear direction toward personalized or precision medicine.

Intraoperative Shave Technique Proves Effective in Breast-Conserving Surgery

Intraoperative Shave Technique Proves Effective in Breast-Conserving Surgery

March 8th 2019

Data from the SHAVE and SHAVE2 trials, in terms of long-term outcomes vis-à-vis local recurrence, may lend some insight into the impact of adjuvant therapy on reducing the ramifications of a positive margin.

Dr. Gertz on the Outlook for Waldenstrom Macroglobulinemia

Dr. Gertz on the Outlook for Waldenstrom Macroglobulinemia

March 4th 2019

Morie A. Gertz, MD, MACP, discusses the current outlook for patients with Waldenström macroglobulinemia.

Newer Agents Extend Survival and Reduce Toxicity in CLL

Newer Agents Extend Survival and Reduce Toxicity in CLL

March 4th 2019

New agents in chronic lymphocytic leukemia are significantly strengthening the armamentarium, particularly next-generation BTK and PI3K inhibitors, and although toxicities remain an issue, tolerability may be improving.

AML Management Evolving for Elderly Patients

AML Management Evolving for Elderly Patients

March 3rd 2019

More options are available than ever before for treating older patients with acute myeloid leukemia and fresh hopes are resting on combinations of venetoclax plus hypomethylating agents.

Agents Emerging in Late Relapsed/Refractory Myeloma Space

Agents Emerging in Late Relapsed/Refractory Myeloma Space

March 3rd 2019

Sagar Lonial, MD, discusses some of the emerging agents for the treatment of patients with late relapse in multiple myeloma.

Watch-and-Wait Approach Can Be Beneficial Strategy in MCL

Watch-and-Wait Approach Can Be Beneficial Strategy in MCL

March 3rd 2019

Prognostic indices for mantle cell lymphoma are good for classifying patients but do little in the way of guiding treatment, and often the best course of action is to watch and wait.

Chemotherapy Poised to Have Minor Role in Future CLL Treatment

Chemotherapy Poised to Have Minor Role in Future CLL Treatment

March 3rd 2019

The day is approaching that chemotherapy may be unnecessary for the treatment of patients with chronic lymphocytic leukemia.

Dr. Wierda Discusses Use of CAR T Cells in CLL

Dr. Wierda Discusses Use of CAR T Cells in CLL

March 2nd 2019

William G. Wierda, MD, PhD, discusses how CAR T cells could become more effective in the treatment of patients with chronic lymphocytic leukemia.

Jabbour Highlights Ongoing Research, Current Treatment for ALL Subtypes

Jabbour Highlights Ongoing Research, Current Treatment for ALL Subtypes

March 2nd 2019

Elias Jabbour, MD, discusses the treatment options for patients with acute lymphoblastic leukemia across these various subgroups.

Dr. Usmani Discusses Management of Early Relapse in Myeloma

Dr. Usmani Discusses Management of Early Relapse in Myeloma

March 2nd 2019

Saad Z. Usmani, MD, FACP, shares his advice for the management of early relapse in patients with multiple myeloma.

Dr. Casulo on Predicting Outcomes in Follicular Lymphoma

Dr. Casulo on Predicting Outcomes in Follicular Lymphoma

March 2nd 2019

Carla Casulo, MD, discusses several different factors that can help predict outcomes in patients with follicular lymphoma.

Making the Case for Earlier CAR T-Cell Therapy in Lymphoma

Making the Case for Earlier CAR T-Cell Therapy in Lymphoma

March 2nd 2019

Real-world data on the use of chimeric antigen receptor T-cell therapy in large B-cell lymphoma bear out the pivotal results from ZUMA-1 and demonstrate not only that the treatment approach is here, but also that it’s time to address issues of efficacy, safety, cost, and moving this approach into earlier lines of therapy.

Targeted Therapies Continue to Show Promise Against FLT3, IDH1/2 Mutations in AML

Targeted Therapies Continue to Show Promise Against FLT3, IDH1/2 Mutations in AML

March 2nd 2019

Jorge E. Cortes, MD, discusses the current treatment options for patients with acute myeloid leukemia, including the use of quizartinib in patients with FLT3 mutations, as well as data from the QuANTUM-R trial.

Dr. Daver Discusses Use of MRD Assessment in Hematologic Malignancies

Dr. Daver Discusses Use of MRD Assessment in Hematologic Malignancies

March 2nd 2019

Naval G. Daver, MD, discusses the role of minimal residual disease assessment in the treatment of patients with hematologic malignancies.

Dr. Park on Challenges With CAR T-Cell Therapies in AML

Dr. Park on Challenges With CAR T-Cell Therapies in AML

March 1st 2019

Jae H. Park, MD, discusses a particular challenge he sees in using CAR T-cell therapies in patients with acute myeloid leukemia.

BCMA-Directed CAR T-Cell Therapy Makes Strong Entrance in Myeloma

BCMA-Directed CAR T-Cell Therapy Makes Strong Entrance in Myeloma

March 1st 2019

B-cell maturation antigen-specific chimeric antigen receptor T-cell therapy is delivering impressive results in multiple myeloma, demonstrating durable responses and acceptable toxicities.

Pre-existing Cardiovascular Disease Linked to Higher Mortality With Abiraterone

Pre-existing Cardiovascular Disease Linked to Higher Mortality With Abiraterone

February 28th 2019

Pre-existing cardiovascular disease was associated with an increased mortality risk during the first 6 months of abiraterone acetate treatment in patients with advanced prostate cancer.

Younger Patients With CRC Misdiagnosed, Diagnosed at Later Stages

Younger Patients With CRC Misdiagnosed, Diagnosed at Later Stages

February 28th 2019

Many younger patients see more than one doctor and face misdiagnoses before being given a diagnosis of colorectal cancer.

Study Validates Speed, Accuracy of Liquid Biopsies Identifying NSCLC Biomarkers

Study Validates Speed, Accuracy of Liquid Biopsies Identifying NSCLC Biomarkers

February 28th 2019

A liquid biopsy test detected all of the guideline-recommended biomarkers in newly diagnosed patients with metastatic non–small cell lung cancer at a similar rate but faster turnaround time to that of tissue genotyping.

Diet May Impact Response to Immunotherapy in Patients With Melanoma

Diet May Impact Response to Immunotherapy in Patients With Melanoma

February 28th 2019

Select patients with melanoma who consume a diet rich in fiber could see an improved response to treatment with immunotherapy.

Iomab-B Shows Promise as Novel Conditioning for HSCT in AML

Iomab-B Shows Promise as Novel Conditioning for HSCT in AML

February 25th 2019

More than 90% of older patients with relapsed/refractory acute myeloid leukemia had successful engraftment of allogeneic hematopoietic stem cell transplant preceded by novel conditioning with an iodinated CD45-targeted antibody.

CD30 CAR T Cells Active in Hodgkin Lymphoma

CD30 CAR T Cells Active in Hodgkin Lymphoma

February 25th 2019

Chimeric antigen receptor T cells targeting CD30 proved to be safe and active in relapsed/refractory Hodgkin lymphoma.

Herpes Zoster Vaccine Elicits Robust Immune Response in HSCT Patients

Herpes Zoster Vaccine Elicits Robust Immune Response in HSCT Patients

February 25th 2019

Two doses of adjuvanted recombinant zoster vaccine following autologous hematopoietic stem cell transplant led to rapid and durable cell-mediated immune responses, results from a subgroup analysis of a large randomized, placebo-controlled trial showed.1