The OncLive® News page includes the latest in clinical oncology news, including breaking regulatory decisions, clinical trial findings, pivotal and practice-changing data published in academic peer-reviewed journals, and more across solid and hematologic malignancies. Regulatory news includes new drug approvals by the FDA and European Union, priority review and breakthrough therapy designations, and orphan drug and fast track statuses.
VICC Receives ‘Exceptional’ Score With Renewal as an NCI-Designated Comprehensive Cancer Center
September 29th 2020Vanderbilt-Ingram Cancer Center received an overall “exceptional” score for its research impact and excellence in patient care. This achievement merits renewed funding from the National Cancer Institute and places it once again in a top group of NCI Comprehensive Cancer Centers.
Pitt & UPMC Hillman Cancer Center Name New Leader of Surgical Oncology
September 25th 2020Following an extensive national search, Amer Zureikat, MD, FACS, has been appointed vice chair of surgery for Surgical Oncology in the Department of Surgery at UPMC and chief of Surgical Oncology at UPMC Hillman Cancer Center.
FDA Grants Priority Review to Crizotinib for Pediatric ALK+ Anaplastic Large Cell Lymphoma
September 23rd 2020The FDA has granted a priority review to a supplemental new drug application for crizotinib in the treatment of pediatric patients with ALK-positive relapsed/refractory systemic anaplastic large cell lymphoma.
OncLive® Names the 2020 Class of Giants of Cancer Care®
September 17th 2020OncLive®, the nation’s leading multimedia resource focused on providing oncology professionals with relevant, insightful information on patient care, is pleased to announce the Eighth Annual Giants of Cancer Care® class of inductees.
Focal Ultrasound Ablation Demonstrates Utility as Primary Therapy in Prostate Cancer
September 15th 2020Hemigland high-intensity focused ultrasound ablation of the prostate was found to be a safe and effective primary treatment for men with localized prostate cancer, leading to continence preservation and suitable short-term disease control.
Emerging Evidence Supports the Use of Narsoplimab in HSCT-TMA
August 31st 2020Rafael F. Duarte, MD, PhD, FRCP, presents 2 real-world clinical cases in which the investigational monoclonal antibody narsoplimab demonstrated clinical benefit in patients with hematopoietic stem cell transplantation-associated thrombotic microangiopathy.
Tipifarnib Exhibits Enriched Activity in HRAS-Mutant Head and Neck Cancer
August 20th 2020Tipifarnib demonstrated encouraging antitumor activity in patients with recurrent and metastatic head and neck cancer with high HRAS-mutant variant allele frequency, surpassing historical competitors in the second- or later-line settings.
Next-Generation Sequencing Shows Marked Potential for Diagnostic Improvements in MPNs
August 13th 2020Patients with a suspected or diagnosed myeloproliferative neoplasm should undergo targeted next-generation sequencing versus sequential or allele specific testing to reduce the risk of identifying a false driver mutation or an excluded diagnosis of MPN.
Novel Triplet Emerges as a Promising Option in BRAF-Mutant Melanoma
August 13th 2020Georgina V. Long, BSc, PhD, MBBS, FRACP, discusses the safety profile of the combination of spartalizumab, dabrafenib, and trametinib, the clinical implications of the biomarker data observed from this trial, and other emerging combinations on the horizon.
FDA Grants Adjuvant Osimertinib Breakthrough Status in Early-Stage EGFR+ NSCLC
July 30th 2020The FDA has granted a breakthrough therapy designation to osimertinib for the adjuvant treatment of patients with stage IB, II, and IIIA EGFR-mutated non–small cell lung cancer following complete resection with curative intent.