The OncLive® News page includes the latest in clinical oncology news, including breaking regulatory decisions, clinical trial findings, pivotal and practice-changing data published in academic peer-reviewed journals, and more across solid and hematologic malignancies. Regulatory news includes new drug approvals by the FDA and European Union, priority review and breakthrough therapy designations, and orphan drug and fast track statuses.
Immunotherapy Combination Receives Breakthrough Designation for Pancreatic Cancer
July 21st 2014The combination of the immunotherapy CRS-207 and the vaccine GVAX Pancreas has received a breakthrough therapy designation from the FDA for its potential as a treatment for patients with metastatic pancreatic cancer.
Trastuzumab-Associated Cardiac Events Reversible, Outweighed by Benefits
July 14th 2014Cardiac events associated with trastuzumab are mostly reversible and outweighed by significant extensions in OS and PFS for patients with HER2-positive breast cancer, according to analyses from several clinical trials exploring the drug.
Value-Based Payment to Overtake Fee-For-Service by 2020
July 1st 2014A new survey by McKesson Health Solutions and released at America's Health Insurance Plan's Institute 2014 conference examined the state of value-based reimbursement, and found that of the existing value-based models, payers and hospitals/health systems predict pay-for-performance (P4P) will experience the most growth
Patricia M. LoRusso, DO, Joins Yale Cancer Center to Further Innovation in Cancer Research
July 1st 2014Patricia M. LoRusso, DO, widely-regarded as a leading expert on developing new cancer drugs through clinical trials, will join Yale Cancer Center in August as a Professor of Medicine and Associate Director of Innovative Medicine at Yale Cancer Center.
ODAC Votes Against Maintenance Olaparib in BRCA-Positive Ovarian Cancer
June 25th 2014The FDA's Oncologic Drugs Advisory Committee voted 11-2 against the accelerated approval of the PARP inhibitor olaparib as a maintenance therapy for women with platinum-sensitive relapsed ovarian cancer with germline BRCA mutations.
340B Drug Program Under Scrutiny
June 25th 2014Hospitals, community health centers, and clinics that participate in the federal 340B drug pricing program are finding themselves under scrutiny from some members of Congress and the pharmaceutical industry because of recent expansion of the Affordable Care Act.
A Third of Practice Managers Surveyed Expect Value-based Contracts to Hurt Bottom Line
June 19th 2014A third of practice managers and health care executives who participated in a survey about value-based contracts said they expected the agreements to hurt the bottom line of their institution or practice