The OncLive® News page includes the latest in clinical oncology news, including breaking regulatory decisions, clinical trial findings, pivotal and practice-changing data published in academic peer-reviewed journals, and more across solid and hematologic malignancies. Regulatory news includes new drug approvals by the FDA and European Union, priority review and breakthrough therapy designations, and orphan drug and fast track statuses.
Preventative Ovarian Surgery in BRCA1 Mutation Carriers More Beneficial Before Age 35
February 24th 2014For the first time, physicians have a clearer understanding of the optimum age for prophylactic oophorectomy in patients with BRCA mutations who want to reduce their risk of ovarian, fallopian tube, and breast cancer.
Weber Explores Advances in Metastatic Melanoma
February 21st 2014In an interview with OncLive, Jeffrey S. Weber, MD, PhD, from the Moffitt Cancer Center, University of South Florida, Tampa, explored the utilization of molecular and immune-targeted therapies as treatments for patients with advanced melanoma.
Physician Practices, Health Care Organizations See Own Staff as Source of Security Breaches
February 21st 2014Results from the final report of the 2013 Healthcare Information and Management Systems Society (HIMSS) Security Survey suggest that physician practices and health care organizations such as hospitals view their own staff members as the greatest source of patient information and confidentiality security breaches.
CMS Bows to Pressure-Conducts End-to-End Testing of ICD-10
February 20th 2014The Centers for Medicare & Medicaid Services (CMS) is caving to pressure from the American Hospital Association, the American Medical Association, and the Medical Group Management Association (MGMA) to conduct far more extensive end-to-end testing to assure proper adjudication and payment of claims as the October 1 deadline for the ICD-10 transition looms
Ramucirumab Combination Improves OS and PFS in NSCLC
February 19th 2014The second-line administration of ramucirumab in combination with docetaxel has shown a statistically significant improvement in overall survival and progression-free survival compared with placebo plus docetaxel in patients with non-small cell lung cancer
Providing Earlier Palliative Care Improves Quality of Life, Patient Satisfaction
February 19th 2014Traditionally, palliative care for patients with cancer is geared towards end-of-life measures, but a new study from the Princess Margaret Cancer Center in Toronto suggests patients who receive palliative care earlier in their cancer therapy report improved quality of life and greater satisfaction.
Reducing the Costs of Cancer Might Involve 'Physician Heal Thyself'
February 14th 2014To reduce the costs of cancer, community oncologists increase the use of evidence-based treatments, standardize care with pathways, transition away from fee-for-service, and change communication with patients about reasonable end-of-life care.
Ease of Enrollment, Efficiency Key Factors in Oncologists' Perception of Patient Assistance Programs
February 12th 2014Biopharmaceutical companies that administer patient assistance programs (PAPs) well in terms of service and support parameters seem to benefit from a halo effect among their oncologist customers, according to "PAP Utilization in Cancer Care," a Cogent Reports survey from Market Strategies International, a market research company.
EHR Meaningful Use Deadline Pushed to March 31
February 11th 2014Providers who are eligible to participate in the Centers for Medicare & Medicaid Services (CMS) electronic health record (EHR) incentive program have a one month reprieve to show that their practices are using the technology in a meaningfully useful way.
Insurers in Government-Run Exchanges to Expand Provider Networks by 30% in 2015
February 5th 2014A news story from Bloomberg Business News suggests that insurers who are participating in government-run health insurance exchanges will be required to increase "essential community providers" in their local geographic area by 30% by 2015.
Current Physician Compensation Models Prevent Shift to Pay-for-Value
February 4th 2014Although new physician compensation models promote pay-for-value, episodic bundles, and risk-adjusted bundles, physicians in non-solo practices are compensated using four methods: base salary, compensation based on personal productivity, compensation based on practice financial performance, and bonus based on factors other than personal productivity and practice financial performance.
Eltrombopag Receives Breakthrough Therapy Designation for Severe Aplastic Anemia
February 3rd 2014Eltrombopag has received a Breakthrough Therapy designation from the FDA for the treatment of cytopenias in patients with severe aplastic anemia who have had insufficient response to immunosuppressive therapy.
Lenvatinib Extends PFS in Differentiated Thyroid Cancer
February 3rd 2014The phase III SELECT trial of the investigational agent lenvatinib (E7080) met its primary endpoint of progression-free survival (PFS) in patients with radioiodine-refractory differentiated thyroid cancer (RR-DTC), according to Eisai Inc., the company that is developing the agent.
Phase II Palbociclib Results Confirm Effectiveness in Breast Cancer
February 3rd 2014Final results from the phase II PALOMA-1 trial continue to support the dramatic efficacy of palbociclib plus letrozole in postmenopausal patients with locally advanced or newly diagnosed estrogen receptor ER-positive, HER2-negative metastatic breast cancer.
An Enhanced Health Information Exchange Manages Costs and Improves Care
January 31st 2014Creating an enhanced, common health information exchange (HIE) pipeline where clinicians, payers, and patients share structured information from multiple electronic medical record/electronic record platforms would effectively manage costs and enhance patient care in oncology, according to a recent paper published in the Journal of Oncology Practice.
Survey of First-year ACOs Reveals Operational Challenges with CMS Data
January 29th 2014Accessing and processing data from the Centers for Medicare & Medicaid (CMS) is the leading operational challenge faced by accountable care organizations (ACOs), according to a large-scale survey conducted by the National Association of ACOs.