The OncLive® News page includes the latest in clinical oncology news, including breaking regulatory decisions, clinical trial findings, pivotal and practice-changing data published in academic peer-reviewed journals, and more across solid and hematologic malignancies. Regulatory news includes new drug approvals by the FDA and European Union, priority review and breakthrough therapy designations, and orphan drug and fast track statuses.
New ASCO Guideline Expands Recommendation for SLN Biopsy Use in Early Stage Breast Cancer
April 11th 2014An updated guideline from ASCO regarding the use of sentinel lymph node (SLN) biopsy in early stage breast cancer supports the use of the procedure over axillary lymph node dissection (ALND) in a larger group of patients than previously recommended.
Medicare Data Reveals Top Billing Docs
April 9th 2014Buckling to calls for transparency and a Wall Street Journal court case requiring the agency to provide public access to physician billing records, the Centers for Medicare & Medicaid Services (CMS) released a database containing transactions worth $77 billion by 880,000 physicians and physician practices certified to collect from Medicare
MAGE-A3 Vaccine Falters in Large Phase III NSCLC Study
April 2nd 2014The large phase III MAGRIT study investigating the MAGE-A3-specific vaccine GSK1572932A for patients with non-small cell lung cancer (NSCLC) will be completely halted following an interim analysis that demonstrated a lack of benefit.
Temporary SGR Patch Expected to Clear Senate Vote
March 31st 2014The Senate is expected to consider and vote on a bill passed by the House on March 27 that includes language to patch the sustainable growth rate (SGR) formula for 12 months and delay ICD-10 implementation until at least October 1, 2015
FDA Panel Narrowly Supports New CRC Blood Test
March 27th 2014The blood-based colorectal cancer (CRC) screening test Epi proColon passed the scrutiny of the FDA's Molecular and Clinical Genetics advisory panel in a close 5-4 vote with 1 abstention in support of the claim that the test's benefits outweigh its risks
MAGE-A3 Antigen-Specific Vaccine Fails to Extend DFS in NSCLC
March 20th 2014The MAGE-A3-specific immunotherapeutic GSK1572932A failed to significantly extend disease-free survival (DFS) in patients with resected nonmetastatic non-small cell lung cancer (NSCLC) who tested negative for a specific gene expression signature
Nivolumab Delivers Durable Remissions With Low Toxicity in Advanced Melanoma
March 14th 2014Nivolumab, a PD-1-specific antibody, has been shown to produce long-term remissions with limited toxicity in patients with advanced melanoma, according to results from one of the longest follow ups to examine the drug.