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Updated INDIGO data reveal that vorasidenib continues to showcase improved efficacy over placebo in patients with IDH1/2-mutated diffuse glioma.

Vorasidenib Shows Consistent Efficacy With Manageable Safety in IDH1/2-Mutant Diffuse Glioma

Tovorafenib generated durable drug holiday responses in pediatric patients with BRAF-altered relapsed/refractory low-grade glioma.

Tovorafenib Leads to Durable Off-Treatment Responses in Pediatric BRAF-Altered R/R Low-Grade Glioma

Early safety findings from the phase 2b RESTORE study (NCT03862430) of NanO2 plus radiation and temozolomide in newly diagnosed glioblastoma were shared.

NanO2 Plus Radiation/Temozolomide Is Under Exploration in Newly Diagnosed Glioblastoma

J. Bradley Elder, MD, discusses blinded early-safety data from a phase 2b trial of IGV-001 in patients with newly diagnosed glioblastoma.

Dr Elder on the Initial Safety Profile of IGV-001 in Newly Diagnosed Glioblastoma

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Kristi Rosa joined MJH Life Sciences in 2016 and has since held several positions within the company. She helped launch the rapidly growing infectious disease news resource 

. Prior to working at the company, she served as lead copywriter and marketing coordinator at The Strand Theater. Email: krosa@onclive.com

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Jax DiEugenio joined MJH Life Sciences in 2024, first as an editorial intern before transitioning into a full-time assistant editor for 

. A recent College of New Jersey graduate, Jax majored in Journalism/ Professional Writing with minors in Public Health and Anthropology. He is also pursuing a Master's Degree in Public Health, concentrating on health communications.

Kyle Doherty joined MJH Life Sciences in 2021 and is the lead editor for 

as well as news and conference updates for OncLive.com. Email: kdoherty@mjhlifesciences.com

Zanidatamab scores approval for HER2+ biliary tract cancer, Versamune HPV is under exploration in HPV16+ head and neck squamous cell carcinoma, and more.

The OncFive: Top Oncology Articles for the Week of 11/17


Gina Mauro is your lead editorial contact for 

. She joined the company in 2015 and has held various positions on 

; she is also the on-air correspondent for 

. Prior to joining MJH Life Sciences, she worked at Gannett as a full-time reporter with the Asbury Park Press. Email: gmauro@onclive.com 

IGV-001, an autologous cell immunotherapy, demonstrated an acceptable safety profile in patients with newly diagnosed glioblastoma.

IGV-001 Showcases Positive Benefit-Risk Profile in Newly Diagnosed Glioblastoma

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My Treatment Approach: Graft vs Host Disease

Videos

Nelson J. Chao, MD, MBA, discusses the treatment of acute and chronic graft-versus-host disease through the lens of two patient profiles.

Nelson J. Chao, MD, MBA, presents the patient profile of a 60-year-old man with chronic myeloid leukemia and graft-versus-host disease (GVHD) and shares his initial impressions.

Patient Profile Presentation: A 60-Year-Old Man with Graft-Versus-Host Disease (GVHD)				

Dr Nelson J. Chao reviews how chronic graft-versus-host disease is diagnosed and staged, and the importance of multidisciplinary team communication.

Staging of Chronic GVHD

Nelson J. Chao, MD, MBA, explains the frontline treatment options for chronic GVHD, and when to consider restarting an immunosuppressive regimen.

First-Line Treatment Options for Patients with Chronic GVHD

Dr Nelson J. Chao presents the patient profile of a 67-year-old woman with chronic graft-versus-host disease after a bone marrow donation from a multiparous female.

Patient Profile Presentation: A 67-Year-Old Woman with GVHD

Nelson J. Chao, MD, MBA, details some novel agents being developed for the systemic treatment of GVHD, particularly chronic GVHD.

Investigational Systemic Treatment Options for GVHD

Dr Nelson J. Chao reviews treatment sequencing and speculates on the future of the GVHD treatment landscape.

Treatment Sequencing and Future of GVHD

Pashna Munshi, MD, presents the patient profile of a 44-year-old woman with acute myeloid leukemia diagnosed with grade 2 skin acute GVHD, and shares her initial impressions and what she might have done differently.

Patient Profile Presentation: A 44-Year-Old Woman With Acute Myeloid Leukemia and Graft-Versus-Host Disease (GVHD)

Dr Pashna Munshi describes for what myeloid malignancies allogeneic transplantation is indicated, and its curative potential.

Indications for Allogeneic Stem Cell Transplantation in the Treatment of Myeloid Malignancies

Pashna Munshi, MD, details how age and risk factors into her choice of conditioning regimen for patients with GVHD receiving allogeneic transplant.

Tailored Conditioning Regimens for Patients with GVHD Receiving Allogeneic Transplant

Dr Pashna Munshi explains the currently available options for GVHD prophylaxis and which regimens she utilizes the most in her clinical practice.

Currently Available Options for GVHD Prophylaxis

Pashna Munshi, MD, reviews the differences between acute and chronic GVHD.

Comparing Acute and Chronic GVHD

Pashna Munshi, MD, discusses how acute GVHD is staged and graded, and the common frontline treatment options.

Available Frontline Treatment Options for Patients With Acute GVHD

Closing her discussion, Dr Pashna Munshi reviews recent data on the available treatment options for patients with steroid-refractory acute GVHD.

Currently Available Options for GVHD Prophylaxis

EP: 1.Patient Profile Presentation: A 60-Year-Old Man with Graft-Versus-Host Disease (GVHD)

EP: 2.Staging of Chronic GVHD

EP: 3.First-Line Treatment Options for Patients with Chronic GVHD

EP: 4.Patient Profile Presentation: A 67-Year-Old Woman with GVHD

EP: 5.Investigational Systemic Treatment Options for GVHD

EP: 6.Treatment Sequencing and Future of GVHD

EP: 7.Patient Profile Presentation: A 44-Year-Old Woman With Acute Myeloid Leukemia and Graft-Versus-Host Disease (GVHD)

EP: 8.Indications for Allogeneic Stem Cell Transplantation in the Treatment of Myeloid Malignancies

EP: 9.Tailored Conditioning Regimens for Patients with GVHD Receiving Allogeneic Transplant

EP: 10.Currently Available Options for GVHD Prophylaxis

EP: 11.Comparing Acute and Chronic GVHD

EP: 12.Available Frontline Treatment Options for Patients With Acute GVHD

EP: 13.Current Treatment Options for Patients with Steroid-Refractory Acute GVHD

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