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Opinion|Videos|July 17, 2024

Factors Driving 3L Therapeutic Selection for mCRC

Author(s)John Marshall, MD, Al B. Benson III, MD, FACP, FACCC, FASCO , Kristen Ciombor, MD, MSCI

Key opinion leaders explore treatment selection for third-line metastatic colorectal cancer patients, examining factors influencing therapy choice with particular focus on comparing fruquintinib to TAS-102 (with or without bevacizumab).

Episodes in this series

5 KOLs are featured in this panel.

EP. 1 Overview of Molecular Testing and Barriers in mCRC

5 KOLs are featured in this panel.

EP. 2 Clinical Considerations for 2L Treatment Sequencing in mCRC

5 KOLs are featured in this panel.

EP. 3 Novel Combination Regimens for 2L mCRC: Insights from ASCO 202

5 KOLs are featured in this panel.

EP. 4 Exploring Toxicities for Second Line Treatments in mCRC

5 KOLs are featured in this panel.

EP. 5 Existing Challenges for Patients Receiving 3L+ Therapies in mCRC

5 KOLs are featured in this panel.

EP. 6 Factors Driving 3L Therapeutic Selection for mCRC

5 KOLs are featured in this panel.

EP. 7 Exploring Data Outcomes From the SUNLIGHT Trial

5 KOLs are featured in this panel.

EP. 8 Fruquintinib for mCRC: Data from the FRESCO & FRESCO-2 Studies

5 KOLs are featured in this panel.

EP. 9 Examining the Evolving 3L Treatment Landscape for mCRC

5 KOLs are featured in this panel.

EP. 10 Additional Key Takeaways of ASCO 2024 Data in mCR

5 KOLs are featured in this panel.

EP. 11 Future Outlooks in the Treatment of Metastatic Colorectal Cancer

Dr Marshall to Panel:Please outline your approach to treatment selection for patients with mCRC in the 3L setting and discuss factors influencing your choice of therapy.
1. Dr Cohen: In which patients would you consider fruquintinib versus TAS-102 ± bevacizumab?
  1. Dr Marshall: For which patients would you deviate from this approach and why you might make this decision?

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