Pirtobrutinib in the Management of R/R CLL: Updates from the BRUIN Trial

Panelists discuss how the non-covalent BTK inhibitor pirtobrutinib has shown promising results in the BRUIN clinical trials for both BTK inhibitor-naive and previously treated chronic lymphocytic leukemia patients, reviewing key efficacy and safety data presented at recent hematology conferences.

EP: 1.The Current Treatment Landscape for R/R CLL

EP: 2.Impact of Prior BTKi vs BCL2i Therapy on Treatment Decision-Making in CLL

EP: 3.Key Patient-Specific Factors Guiding Treatment Selection in CLL

EP: 4.Tailoring Treatment Approaches for Rapid vs. Slow Disease Progression in CLL

EP: 5.Assessing Resistance to First-Line BTK Inhibitor Therapy: The Emergine Role of Testing in CLL

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EP: 6.Pirtobrutinib in the Management of R/R CLL: Updates from the BRUIN Trial

EP: 7.Application of Pirtobrutinib in R/R CLL: Expert Perspectives

EP: 8.Influence of TLS Risk and Patient Preferences on Treatment Selection in Relapsed/Refractory CLL

EP: 9.Navigating treatment strategies for patients with multi-refractory CLL: CAR-T, ASCT, and PI3K Inhibitors

EP: 10.Sequencing and Combination Strategies with Pirtobrutinib and CAR-T Therapy in R/R CLL

EP: 11.Treatment Sequencing in Relapsed/Refractory CLL: Key Factors Influencing Decision-Making

EP: 12.Emerging role of doublet triplet therapies in R/R CLL: Expert Perspectives

EP: 13.The Impact of Emerging Resistance Patterns on Treatment Sequencing in R/R CLL

EP: 14.Multidisciplinary Approach to Managing Treatment for Relapsed/Refractory CLL

Video content above is prompted by the following:

• To briefly review the non-covalent BTKi pirtobrutinib and BRUIN data.
  • Pirtobrutinib (BRUIN) – BRUIN BTKi Naive EHA 2024; BRUIN prior BTKi

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