Opinion

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Sequencing and Combination Strategies with Pirtobrutinib and CAR-T Therapy in R/R CLL

Panelists discuss how they approach treatment selection for multi-refractory chronic lymphocytic leukemia (CLL) patients, considering factors such as prior therapy responses, patient fitness, and disease characteristics to guide choices among available options, including CAR T-cell therapy, while also addressing the limitations and challenges associated with each treatment modality in their decision-making process.

Video content above is prompted by the following:

  • Which treatment options do you offer to your multi-refractory CLL patients and how do you select among available therapies?
  • What key factors guide your decision to use CAR T-cell therapy in the R/R setting and what criteria do you use to select patients for this treatment?
  • What are some limitations or challenges associated with these therapies and how do you weigh these into your
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