Latest Conference Articles

The OncLive® Conference page includes a listing of all conferences covered by OncLive®, including the ASCO, ESMO, SITC, EHA, ASH, and SABCS annual meetings, as well as the Chemotherapy Foundation Symposium and Miami Breast Cancer Conference, among many others. Conference coverage incorporates articles and interviews in written and video format.

Dr. Oxnard Discusses the Circulating Cell-Free Genome Atlas Study

Dr. Oxnard Discusses the Circulating Cell-Free Genome Atlas Study

June 3rd 2018

Geoffrey R. Oxnard, MD, associate professor of medicine, Harvard Medical School, thoracic oncologist, medical oncology, Dana-Farber Cancer Institute, discusses the design and importance of the Circulating Cancer Genome Atlas (CCGA) study in an interview with OncLive during the 2018 ASCO Annual Meeting.

Dr. Costa on Triplet of Venetoclax, Carfilzomib, and Dexamethasone in Multiple Myeloma

Dr. Costa on Triplet of Venetoclax, Carfilzomib, and Dexamethasone in Multiple Myeloma

June 3rd 2018

Luciano J. Costa, MD, PhD, associate professor of medicine, Blood and Marrow Transplantation and Cell Therapy Program, University of Alabama at Birmingham School of Medicine, discusses phase II findings with the triplet regimen of venetoclax (Venclexta), carfilzomib (Kyprolis), and dexamethasone in patients with relapsed/refractory multiple myeloma. Costa shared this insight in an interview with OncLive during the 2018 ASCO Annual Meeting.

Matched Targeted Therapy Extends Survival in Advanced Hard-to-Treat Cancers

Matched Targeted Therapy Extends Survival in Advanced Hard-to-Treat Cancers

June 2nd 2018

Personalized therapy based on tumor molecular profiling resulted in improved overall survival for patients with advanced, hard-to-treat cancers.

cfDNA Assays Demonstrate High Specificity for Early Stage Lung Cancer Detection

cfDNA Assays Demonstrate High Specificity for Early Stage Lung Cancer Detection

June 2nd 2018

Initial results from the Circulating Cell-Free Genome Atlas study strongly suggest that cell-free DNA tests can be used with a high degree of specificity to detect signs of early stage lung cancer.

Pembrolizumab Studies Show Disparate Data on Link Between AE and Response in Multiple Myeloma

Pembrolizumab Studies Show Disparate Data on Link Between AE and Response in Multiple Myeloma

June 2nd 2018

Pembrolizumab (Keytruda) yielded inconsistent results regarding the relationship between immune-related adverse events and objective response in multiple myeloma.

Microsatellite Instability Status Links to Lynch Syndrome in Broad Array of Cancers

Microsatellite Instability Status Links to Lynch Syndrome in Broad Array of Cancers

June 2nd 2018

Microsatellite instability-high tumors are more likely to be associated with the presence of Lynch syndrome. Yet, 45% of patients with cancers not typically identified with Lynch syndrome actually qualify for germline genetic testing.

Only Modest Benefit Seen With Taselisib in PIK3CA-Mutant Breast Cancer

Only Modest Benefit Seen With Taselisib in PIK3CA-Mutant Breast Cancer

June 2nd 2018

Treatment with taselisib in combination with fulvestrant provided a modest progression-free survival benefit of 2 months compared with fulvestrant alone in patients with estrogen receptor–positive, PIK3CA-mutant locally advanced or metastatic breast cancer

Once Weekly Carfilzomib Superior in Relapsed/Refractory Myeloma

Once Weekly Carfilzomib Superior in Relapsed/Refractory Myeloma

June 2nd 2018

Carfilzomib (Kyprolis) administered once weekly at 70 mg/m2 with dexamethasone resulted in a prolonged PFS compared with the standard twice-weekly schedule in patients with relapsed/refractory multiple myeloma.

Atezolizumab Plus Chemo Extends PFS in Frontline Squamous NSCLC

Atezolizumab Plus Chemo Extends PFS in Frontline Squamous NSCLC

June 2nd 2018

The addition of atezolizumab (Tecentriq) to frontline carboplatin and nab-paclitaxel (Abraxane) delayed the risk of progression or death by 29% compared with chemotherapy alone for patients with advanced squamous NSCLC.

LOXO-292 Shows Impressive Response Rates for RET-Positive Tumors

LOXO-292 Shows Impressive Response Rates for RET-Positive Tumors

June 2nd 2018

The highly-selective RET inhibitor LOXO-292 demonstrated robust clinical activity across RET-altered solid tumors, including in patients with brain metastases and the RET V804M gatekeeper mutation.

Ibrutinib/Rituximab Reduces Progression Risk by 80% in Waldenstrom Macroglobulinemia

Ibrutinib/Rituximab Reduces Progression Risk by 80% in Waldenstrom Macroglobulinemia

June 2nd 2018

Adding ibrutinib to rituximab lowered the risk of disease progression or death by 80% versus rituximab alone in patients with Waldenström macroglobulinemia.

bb2121 Adds Nearly 1 Year of PFS for Heavily Pretreated Myeloma

bb2121 Adds Nearly 1 Year of PFS for Heavily Pretreated Myeloma

June 2nd 2018

bb2121 had a median progression-free survival of 11.8 months and a median duration of response of 10.8 months for patients with relapsed/refractory heavily pretreated multiple myeloma.

Dr. Mohile on Using a Geriatric Assessment in Older Patients With Cancer

Dr. Mohile on Using a Geriatric Assessment in Older Patients With Cancer

June 2nd 2018

Supriya Gupta Mohile, MD, MS, professor of medicine and surgery, James Wilmot Cancer Institute, director, Geriatric Oncology Clinic, University of Rochester, discusses pooled findings with a geriatric assessment for older patients with cancer in an interview with OncLive during the 2018 ASCO Annual Meeting.

Dr. George on Results of Abi Race Trial in Prostate Cancer

Dr. George on Results of Abi Race Trial in Prostate Cancer

June 2nd 2018

Daniel J. George, MD, professor of medicine, surgery, member, Duke Cancer Institute, discusses the results of the prospective multicenter Abi Race trial, which compared outcomes of African-American and Caucasian patients with metastatic castration-resistant prostate cancer (mCRPC) treated with abiraterone acetate (Zytiga) and prednisone.

Pomalidomide Triplet Extends PFS in Relapsed/Refractory Myeloma

Pomalidomide Triplet Extends PFS in Relapsed/Refractory Myeloma

June 2nd 2018

Adding pomalidomide (Pomalyst) to bortezomib (Velcade) and low-dose dexamethasone reduced the risk of disease progression or death by 39% in patients with relapsed/refractory multiple myeloma with prior exposure to lenalidomide.

Venetoclax/Carfilzomib Combo Highly Effective for t(11;14) Myeloma

Venetoclax/Carfilzomib Combo Highly Effective for t(11;14) Myeloma

June 2nd 2018

The addition of venetoclax to carfilzomib and dexamethasone demonstrated a 100% objective response rate with a very good partial response or better rate of 86% for patients with relapsed/refractory t(11;14) multiple myeloma.

Colorectal Cancer Treatment Twice as Costly in US Than Canada, Despite Similar Outcomes

Colorectal Cancer Treatment Twice as Costly in US Than Canada, Despite Similar Outcomes

June 2nd 2018

A study that compared costs of treatment for metastatic colorectal cancer in Western Washington and the province of British Columbia in Canada found that prices were more than twice as high for the US patients than for their Canadian counterparts, with no significant difference in outcomes.

Geriatric Assessment Improves Patient Satisfaction, Patient-Oncologist Communication

Geriatric Assessment Improves Patient Satisfaction, Patient-Oncologist Communication

June 2nd 2018

Evaluating health-related concerns as part of routine care for elderly patients with advanced cancer significantly improved doctor-patient communication and patient satisfaction.

Black Men May Fare Better Than White Men With Standard mCRPC Therapy

Black Men May Fare Better Than White Men With Standard mCRPC Therapy

June 2nd 2018

Black men with metastatic castration-resistant prostate cancer may experience greater benefits from chemotherapy and hormone-targeting treatment than their white counterparts.

Compared With Men, Women With Head and Neck Cancer Undertreated

Compared With Men, Women With Head and Neck Cancer Undertreated

June 1st 2018

Women with head and neck cancer may be severely undertreated and have higher death rates compared with their male counterparts.

ASCO 2018: Top Oncologists Select Key, Practice-Changing Abstracts

ASCO 2018: Top Oncologists Select Key, Practice-Changing Abstracts

May 30th 2018

Key opinion leaders spoke with OncLive ahead of the 2018 ASCO Annual Meeting to share the top abstracts they believe could have the greatest impact on clinical practice and patient outcomes across lymphomas, gastrointestinal cancers, genitourinary cancers, and lung cancer.

NGS Established as Most Cost-Effective Genetic Test for Metastatic NSCLC

NGS Established as Most Cost-Effective Genetic Test for Metastatic NSCLC

May 17th 2018

Next-generation sequencing in metastatic non-small cell lung cancer can save Center for Medicare and Medicaid Services payers $1.4 million to $2.1 million.

Symptom Tracking System Reduces Severity in Patients With Head and Neck Cancer

Symptom Tracking System Reduces Severity in Patients With Head and Neck Cancer

May 17th 2018

Patients who used mobile and sensor technology to track their symptoms demonstrated reduced severity of their symptoms compared with patients who received standard care.

Despite USPSTF Recommendations and Medicaid Coverage, Data Show Low Lung Cancer Screening Rate

Despite USPSTF Recommendations and Medicaid Coverage, Data Show Low Lung Cancer Screening Rate

May 17th 2018

A total 1.9% of more than 7.6 million current and former heavy smokers in the United States underwent lung cancer screening in 2016, suggesting that it remains inadequate despite USPTF recommendations.

Shorter Trastuzumab Duration Matches 12-Month Standard for Early HER2+ Breast Cancer

Shorter Trastuzumab Duration Matches 12-Month Standard for Early HER2+ Breast Cancer

May 17th 2018

A shorter 6-month course of adjuvant trastuzumab (Herceptin) was found to be noninferior for disease-free survival compared with the standard 12-month schedule for patients with HER2-positive early breast cancer.

Nelarabine Boosts 4-Year DFS Above 90% in Pediatric/AYA T-Cell Cancers

Nelarabine Boosts 4-Year DFS Above 90% in Pediatric/AYA T-Cell Cancers

May 17th 2018

Adding nelarabine to escalating-dose methotrexate induced a 4-year disease-free survival rate of 91% in a cohort of pediatric and young adult patients with newly diagnosed T-cell cancers.

Cognitive Behavior Therapy, Acupuncture Improve Insomnia Symptoms in Cancer Survivors

Cognitive Behavior Therapy, Acupuncture Improve Insomnia Symptoms in Cancer Survivors

May 17th 2018

Both cognitive behavior therapy for insomnia (CBT-I) and acupuncture produced clinically meaningful improvements in insomnia severity scores for cancer survivors, but data from the randomized CHOICE clinical trial showed that CBT-I was more effective overall for reducing the severity of insomnia.

Expert Explains State of TKI Treatment in Pediatric CML

Expert Explains State of TKI Treatment in Pediatric CML

May 10th 2018

Discontinuation of tyrosine kinase inhibitor treatment may be a possibility for children with chronic myeloid leukemia and, because they could be on-treatment for decades, treatment-free remission is even more important for pediatric patients than for adults.

Eltrombopag Improves Platelet Count in Pediatric HIV

Eltrombopag Improves Platelet Count in Pediatric HIV

May 8th 2018

Eltrombopag (Promacta) boosted the platelet count in a 13-year-old boy with HIV-associated thrombocytopenia, according to case study results presented at the 2018 American Society of Pediatric Hematology/Oncology Conference.

Dr. Engel on the Use of Eltrombopag in HIV-Related Thrombocytopenia

Dr. Engel on the Use of Eltrombopag in HIV-Related Thrombocytopenia

May 5th 2018

Elissa Engel, MD, pediatric resident, University of South Florida, discusses the successful use of eltrombopag (Promacta) in a pediatric patient with HIV-related thrombocytopenia.