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Your AI-Trained Oncology Knowledge Connection!

Opinion|Videos|August 23, 2024

Clinical scenario 1 - BRAFKIAA-1549 fusion

Author(s)Jason Fangusaro, MD

The panel examines a specific patient case, offering detailed insights into their decision-making process and treatment approaches for patients with pediatric low-grade gliomas (pLGG).

Episodes in this series

3 KOLs are featured in this series.

EP. 1 Overview of pLGG presentation and categorization

3 KOLs are featured in this series.

EP. 2 Molecular Characterization of pLGG

3 KOLs are featured in this series.

EP. 3 Less Common Molecular Alterations in pLGG and Testing Recommendations

3 KOLs are featured in this series.

EP. 4 Standard of care for frontline treatment of non-V600E-specific pLGG tumors

3 KOLs are featured in this series.

EP. 5 Ongoing clinical trials for frontline treatment of non-V600E-specific pLGG tumors

3 KOLs are featured in this series.

EP. 6 Current Treatment of Patients with NF1 pLGG

3 KOLs are featured in this series.

EP. 7 Standard of Care Pptions Specific for Frontline Treatment of BRAF V600E-Mutated pLGG

3 KOLs are featured in this series.

EP. 8 Treatment Considerations for Progressive pLGG

3 KOLs are featured in this series.

EP. 9 Radiation and Targeted Therapies for Progressive pLGG

3 KOLs are featured in this series.

EP. 10 The Role of Tovorafenib in Treatment of Progressive pLGG

3 KOLs are featured in this series.

EP. 11 Clinical Trials to Increase Treatment Options in the Progressive Setting

3 KOLs are featured in this series.

EP. 12 Clinical scenario 1 - BRAFKIAA-1549 fusion

3 KOLs are featured in this series.

EP. 13 Alternatives and Considerations for Clinical Scenario 1

3 KOLs are featured in this series.

EP. 14 Clinical Scenario 2 - BRAFV600E

3 KOLs are featured in this series.

EP. 15 Potential Adverse Events With Targeted Therapies

3 KOLs are featured in this series.

EP. 16 Clinical Insights: Looking Forward for pLGG

Of the possible options, what treatment approach would you select for this patient?
What key clinical or patient-specific factors informed this choice?
Please consider and discuss alternate scenarios:
What if this patient had received frontline chemotherapy (instead of selumetinib) and then progressed? How would this impact your treatment decision?
What if the patient was currently on a MEKi, would you switch?

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