Dr Xu Reviews Data from the CLEAR Trial and Recent Analyses at ASCO 2024 - Lenvatinib + Pembrolizumab in Frontline Advanced RCC

Author(s):

Wenxin (Vincent) Xu, MD, reviews recent analyses from the CLEAR study, which evaluated the combination of lenvatinib and pembrolizumab as a frontline treatment for advanced renal cell carcinoma (RCC).

EP: 1.Treatment Selection in the Frontline Setting of Advanced Clear Cell RCC

EP: 2.Dr Wulff-Burchfield Reviews CheckMate 214 and CheckMate 9ER

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EP: 3.Dr Xu Reviews Data from the CLEAR Trial and Recent Analyses at ASCO 2024 - Lenvatinib + Pembrolizumab in Frontline Advanced RCC

EP: 4.Dr Voss Shares Highlights from the COSMIC-313 and LITESPARK-024 Trials

Please discuss recent analyses from the CLEAR study, evaluating lenvatinib + pembro in frontline advanced RCC.
1. Efficacy by baseline tumor size (Grunwald, et al. ASCO GU 2024. Abstract 364)
2. Biomarker analysis (Motzer et al. ASCO 2024 Abstract 4504)
3. Network meta-analysis– len + pembro vs other 1L treatments in advanced RCC (Grunwald, et al. ASCO GU 2024. Abstract 482)