Latest Conference Articles

New Metastatic Melanoma Therapies Create Hope for Patients, Key Role for Oncology Nurses

The incidence of melanoma, the deadliest of all skin cancers, is quickly rising, and the disease is responsible for more than 8000 deaths each year.

Opportunity Knocks: New ACoS Standard Requires Navigation Process in Place by 2015

Facilities seeking Commission on Cancer accreditation now need to have a patient navigation process in place by 2015.

Beth DuPree, MD, Updates Navigators on Breast Cancer Treatments

Updates on breast cancer risk factors, screening methods, and treatments for the nurse navigators who are guiding patients from diagnosis to treatment and, hopefully, through survivorship.

Cristi Radford on the Nurse Navigator's Role in Genetic Counseling

Cristi Radford, a Certified Genetic Counselor, explains the multifaceted role that oncology nurse navigators play in the genetic counseling process.

Dr. Cohen on the Cabozantinib Dosage and Tolerability

Ezra Cohen, MD, from the University of Chicago Medical Center, discusses the impact of cabozantinib's dose size on tolerability.

Photos From the European Society for Medical Oncology Congress

Photos from the 2012 European Society for Medical Oncology (ESMO) congress, held at the Austria Center Vienna from September 28 to October 2, in Vienna, Austria.

In Refractory GIST, Regorafenib Delays Disease Progression Across All Subgroups

Regorafenib significantly delays disease progression in virtually all subgroups of patients with GIST in the second-line setting, and may even confer benefits when continued after progression.

Long-Term Data Show Significant Improvement in Survival With Ipilimumab in Melanoma

Nearly twice as many patients with metastatic melanoma who received a combination of ipilimumab and dacarbazine were alive after four years, suggesting that ipilimumab has long-term survival benefits.

One Year of Adjuvant Trastuzumab Remains Standard of Care

Long-term follow-up of the HERA trial confirms that 1 year of adjuvant therapy with trastuzumab should remain the standard of care for treatment of women with HER2-positive invasive early breast cancer.

Bevacizumab Plus Chemotherapy Improves Response Rates and PFS in Platinum-Resistant Ovarian Cancer

An exploratory analysis of the phase III AURELIA trial affirms the benefit of adding bevacizumab to chemotherapy for patients with platinum-resistant recurrent ovarian cancer.

No Survival Advantage for Ifosfamide Added to Doxorubicin in Advanced Soft Tissue Sarcoma

The addition of ifosfamide to doxorubicin in the treatment of advanced soft tissue sarcomas delayed disease progression but did not improve survival.

Pazopanib Another Front-Line Therapy Option for Metastatic Renal Cell Carcinoma

Pazopanib appears to be another good option for first-line therapy of metastatic renal cell carcinoma along with sunitinib.

Updated Data Show T-DM1 Improves Overall Survival in HER2-Positive Breast Cancer

An updated analysis of the phase III EMILIA trial showed that T-DM1 significantly extended survival in women with HER2-positive, unresectable, locally advanced or metastatic breast cancer.

Positive Results in ALK-Positive NSCLC With First ALK Inhibitor

Crizotinib extended PFS and improved response rates compared with single-agent chemotherapy with pemetrexed or docetaxel in patients with advanced, previously treated, ALK-positive, NSCLC.

Updated Regorafenib Survival Results Confirm Effectiveness

Patients with heavily pretreated metastatic colorectal cancer who received regorafenib experienced a sustained survival benefit across all prespecified subgroups.

Dr. Ezra Cohen on the Pharmacokinetics of Cabozantinib

Ezra E.W. Cohen, MD, from the University of Chicago Medical Center, on the pharmacokinetics and efficacy of cabozantinib for medullary thyroid cancer.

Does Docetaxel Add Benefit to the Oral Fluoropyrimidine S-1 in Gastric Cancer?

Two analyses, two different conclusions in Asian START trial when docetaxel was added to S-1 for patients with previously untreated advanced or recurrent gastric cancer.

BRAF Inhibitor Plus MEK Inhibitor Encouraging in Metastatic Melanoma

Combining the new drugs dabrafenib and trametinib provided a clinically meaningful improvement in patients with melanoma that had BRAF V600 mutations.

Gefitinib: Small Benefit as Second-Line Therapy in Esophageal Cancer

Gefitinib improved progression-free survival and some quality of life measures when used as second-line therapy for esophageal cancer.

Multikinase Inhibitor Prolongs Progression-Free Survival in MTC

Cabozantinib significantly prolonged progression-free survival in medullary thyroid cancer compared with placebo among patients with radiographically confirmed progressive disease at study onset.

Photos From the American Thyroid Association Annual Meeting

Photos from the 82nd Annual Meeting of the American Thyroid Association held in Quebec City, Canada, on September 19-23, 2012.

Dr. Sippel on the Importance of the Initial Surgery for MTC

Rebecca S. Sippel, MD, from the University of Wisconsin, discusses the importance of the initial surgery for patients with medullary thyroid cancer on outcomes.

Panels of Molecular Markers Improve Diagnosis of Thyroid Cancer

The application of molecular markers is already significantly improving the diagnosis of thyroid cancer and broader application could help prevent unnecessary surgeries to confirm the diagnosis.

BRAF Mutational Status in Papillary Microcarcinoma: Diagnostic and Prognostic Potential

Four histopathologic features of papillary microcarcinoma help predict how aggressive the tumor will be and subsequently how aggressive treatment must be to prevent its spread.

Coverage From the 2012 NCONN Conference

OncLive presents live coverage from the 2012 NCONN Changing the Face of Cancer Care Conference, held at the Gaylord Opryland Hotel from October 4th to 6th, in Nashville, TN.

Dr. Haugen Describes the 82nd Annual ATA Meeting

Dr. Bryan Haugen, from University of Colorado School of Medicine, Describes the 82nd Annual Meeting of the American Thyroid Association.

Dr. Nikiforov on Molecular Testing of Thyroid Nodules

Dr. Yuri Nikiforov, from the University of Pittsburgh, on Molecular Testing to Diagnose Cancerous Thyroid Nodules.

Blanket Approach to RAI in PTC Patients May Not Be Necessary

A blanket approach to the use of radioactive iodine may not be necessary in many patients with papillary thyroid cancer provided they undergo expert total thyroidectomy first.

Disease Stabilization Now Possible in Metastatic MTC With Targeted Therapies

The availability of molecular agents that target oncogenic signaling pathways now offers the possibility of achieving disease stabilization in a proportion of patients with metastatic medullary thyroid cancer.

Initial Operation to Remove Medullary Thyroid Cancer Best Chance for Cure

The initial surgical procedure performed for the management of medullary thyroid cancer is the best chance surgeons have for a cure.