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Opinion|Videos|July 23, 2024

Exploring Biomarker Analysis, Real-World Data, and Quality of Life in LR-MDS: Insights from EHA 2024

Author(s)Guillermo Garcia-Manero, MD, Rami Komrokji, MD, Esther Natalie Oliva, MD

Experts in lower-risk myelodysplastic syndromes analyze and interpret the comparative biomarker data on ring sideroblasts in LR-MDS patients from the COMMANDS study.

Episodes in this series

5 KOLs are featured in this program

EP. 1 Navigating Myelodysplastic Syndromes: Updates to WHO & ICC Guidelines, IPSS-M, and Risk Stratification

5 KOLs are featured in this program

EP. 2 Dr Oliva on Addressing Challenges in Treating Lower-Risk MDS 

5 KOLs are featured in this program

EP. 3 Frontline Therapy for Lower-Risk MDS: Global Perspectives and Treatment Selection Strategies

5 KOLs are featured in this program

EP. 4 Review of the COMMANDS Trial

5 KOLs are featured in this program

EP. 5 Perceptions of the EHA 2024 Full Analysis of the COMMANDs Trial

5 KOLs are featured in this program

EP. 6 Clinical Implications of COMMANDS Trial in Clinical Practice

5 KOLs are featured in this program

EP. 7 Treatment Decision-Making Based on the COMMANDS Trials

5 KOLs are featured in this program

EP. 8 Exploring Biomarker Analysis, Real-World Data, and Quality of Life in LR-MDS: Insights from EHA 2024

5 KOLs are featured in this program

EP. 9 Dr.'s Cluzeau and Komrokji on Utilization Patterns of luspatercept in LR-MDS EHA 2024 Data

5 KOLs are featured in this program

EP. 10 Safety Profile of Available Frontline Treatments LR-MDS

5 KOLs are featured in this program

EP. 11 1L treatment of lower-risk MDS beyond luspatercept

5 KOLs are featured in this program

EP. 12 Sequencing Second-Line Treatments for LR-MDS

5 KOLs are featured in this program

EP. 13 Perspectives of IMerge Study

5 KOLs are featured in this program

EP. 14 Real-World Evidence and Emerging Therapies in Lower-Risk MDS: Insights from EHA 2024

5 KOLs are featured in this program

EP. 15 EHA 2024 Future Directions in Lower-Risk MDS Treatment: Emerging Data, Approvals, and Guideline Updates

5 KOLs are featured in this program

EP. 16 Final Thoughts on EHA 2024 Data for Lower-Risk MDS

What insights can you share on the comparative biomarker analysis on RS in patients with LR-MDS from the COMMANDS study?
Let’s continue our discussion by exploring real-world data and quality of life (QoL) findings in LR-MDS.
- For patients receiving luspatercept or epoetin alfa, how do you interpret the findings surrounding Hgb levels and improving QoL in transfusion-dependent patients with LR-MDS?

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